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1 definition found
 for Softening of the brain
From The Collaborative International Dictionary of English v.0.48 :

  Softening \Sof"ten*ing\,
     a. & n. from Soften, v.
     [1913 Webster]
  
     Softening of the brain, or Cerebral softening (Med.), a
        localized softening of the brain substance, due to
        hemorrhage or inflammation. Three varieties, distinguished
        by their color and representing different stages of the
        morbid process, are known respectively as red, yellow, and
        white, softening.
        [1913 Webster]

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